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Literature summary extracted from

  • Sahi, S.; Tewatia, P.; Ghosal, S.
    Leishmania donovani pteridine reductase 1: comparative protein modeling and protein-ligand interaction studies of the leishmanicidal constituents isolated from the fruits of Piper longum (2012), J. Mol. Model., 18, 5065-5073.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.5.1.33 (2E,4E)-N-(2-methylpropyl)dodeca-2,4-dienamide
-
 Leishmania donovani
1.5.1.33 (2E,4E)-N-(2-methylpropyl)octadeca-2,4-dienamide
-
 Leishmania donovani
1.5.1.33 (2E,4E,12E)-13-(benzo[d][1,3]dioxol-5-yl)-N-isobutyltrideca-2,4,12-trienamide
-
 Leishmania donovani
1.5.1.33 1-(3,4-methylenedioxyphenyl)-(1E)-tetradecene
-
 Leishmania donovani
1.5.1.33 miltefosine
-
 Leishmania donovani
1.5.1.33 N-isobutyl-19-(3',4'-methylenedioxyphenyl)-(2E,4E)-nonadecadienamide
-
 Leishmania donovani
1.5.1.33 piperlongimin A i.e. (2E)-N-isobutyl-hexadecenamide Leishmania donovani
1.5.1.33 piperlongimin B i.e. (2E)-octadecenoylpiperidine Leishmania donovani

Organism

EC Number Organism UniProt Comment Textmining
1.5.1.33 Leishmania donovani
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.5.1.33 amastigote
-
 Leishmania donovani
-
1.5.1.33 promastigote
-
 Leishmania donovani
-

Synonyms

EC Number Synonyms Comment Organism
1.5.1.33 pteridine reductase 1
-
 Leishmania donovani
1.5.1.33 PTR1
-
 Leishmania donovani

Cofactor

EC Number Cofactor Comment Organism Structure
1.5.1.33 NADPH
-
 Leishmania donovani